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You can launch calls from one-on-one or group chats: 
 
 
From your chat list, tap New chat button in the header and enter a name or names. 
 
 
From a chat, tap Video call Video call button or Audio call Calls button. The person you're calling can answer from their desktop or mobile app. 
 
 
You can also start a call from someone's profile card. Open it by tapping their profile picture in a channel or from a search.